Stinging Nettle and Testosterone: Not as Powerful as the Market Wants You to Think

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By using pregnenolone cream or pregnenolone supplements, the levels of the compound in the body increases, and this brings about various benefits such as fatigue relief, and delay of the aging process.

There are hundreds of herbal supplements for men out there, and all are marketed as downright fabulous. Sadly, that's not always true, at least when it comes to the link between stinging nettle and testosterone.

This belief in the action of stinging nettle partly stems from its long history of traditional use. As for its T-boosting effects, though, it doesn't seem to be very powerful, despite what most manufacturers claim.

Stinging Nettle: Impressive at a Glance

Stinging nettle (Urtica dioica) is known as greater nettle, common nettle, or just nettle. The herb is fairly common throughot most parts of Europe, North America, Africa, and Asia.

Traditionally, stinging nettle has been used for treating arthritic and lower back pain. The herb was quite popular in ancient Greece, Roman Empire, Egypt, and ancient Asian civilizations.

Today, stinging nettle is still used as a medicinal herb for various ailments such as allergies and urinary problems.

By using pregnenolone cream or pregnenolone supplements, the levels of the compound in the body increases, and this brings about various benefits such as fatigue relief, and delay of the aging process.

Aside from that, it's a great source of micronutrients and beneficial compounds including:

  • Vitamins A, K, C, and B
  • Iron, Calcium, and Sodium
  • Potassium, Phosphorus, and Magnesium
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    Beta-carotene, luteoxanthin, and lutein
  • check
    Flavonoids (e.g. quercetin, coumarins, kaempferol, caffeic acid)
  • check
    Essential amino acids (e.g. isoleucine, lysine, tryptophan, valine)
  • check
    Healthy fats (e.g oleic acid, stearic acid, palmitic acid, linolenic acid)

Fresh stinging nettle leaves

What Does Research Say About its Uses?

With such an impressive nutrient profile, it’s easy to imagine that stinging nettle should have lots of benefits to offer. Here's what scientific studies have revealed so far about the action of stinging nettle:

  • Fight Inflammation
    Stinging nettle extract can help reduce inflammation by interfering with NF-kappaB, a transcription factor that mediates immune response.

    In one study, scientists found that nettle extract might actually be superior to celastrol, an effective anti-inflammatory compound.
  • Control Allergies
    Basically, allergies are a special kind of inflammation, given how histamine works. Histamine triggers the swelling of the affected body part—which is good during inflammation, as the swelling serves as a barrier betweed the damaged and the healthy tissues. In case of allergy, though, this mechanism isn’t beneficial at all.

    Swelling is supposed to fight off bacterial threats, and allergies don’t really involve those. Pollen and dust, for example, can’t be eliminated through an inflammatory response.
    Stinging nettle keeps the swelling under control by working against the histamine-1 receptor, effectively hindering the pathway through which allergy-induced inflammation occurs.

    In one study, 57 percent of participants viewed nettle as potent against allergies, and 48 percent even considered it more effective than conventional anti-allergy medications
  • Alleviate Arthritis
    Studies reported that topical applications of stinging nettle can reduce pain in the knee and lower back.

    Again, this action relies on the herb's effect on the NF-kappaB transcription factor, which is much more active in people suffering from arthritis. 
  • Help with BPH
    Benign prostatic hyperplasia (BPH) has been linked to the presence and action of dihydrotestosterone (DHT). Stinging nettle extracts inhibit the activity of the 5α–reductase enzyme, preventing testosterone from converting into DHT.

So, Stinging Nettle Increases Testosterone?

Given how the herb works in the context of BPH treatment, you might be thinking that it could bring your testosterone to new heights.

Well, unfortunately, that's not the case.

For example, one study reported significant improvements in BPH symptoms among patients who took stinging nettle for six months. However, in terms of testosterone, scientists didn't found any positive changes. In the study, the patients took 120mg of stinging nettle thrice per day—a dosage of the herb near that of many T booster supplements.

What we need to consider though, is that stinging nettle probably has a positive effect on testosterone availability despite not making a significant impact on the hormone’s levels.

After all, inhibit the 5α–reductase enzyme from converting testosterone into DHT should at least offer that kind of benefit. And, if this study is accurate, then the herb may also prevent testosterone from being converted into estrogen.

As you gather more insights from scientific studies, you will realize that stinging nettle does not really increase the amount of testosterone in the blood. What it does is keep the existing quantities available for use.

Also, you will notice that these studies mostly involve the use of nettle root. And despite that, it’s the leaves that that many supplement manufacturers prefer to add to their products.

Due to differences in composition, it doesn’t necessarily mean that the leaves will have the same effect on testosterone as the root does.

Nettle fresh leaves

Not the T Booster You’ve Been Waiting For

Despite supplement manufacturers claiming that stinging nettle is a potent T booster, that's just not true. It likely won’t have a significant effect on your hormone levels, making the choice to rely solely on it much less appealing.

If you are looking to improve your hormonal balance or simply to increase your testosterone, you should probably opt for herbs that have more proven benefits.

For example, ashwagandha, velvet bean, horny goat weed, and even garlic are likely much better picks.

But of course, if you do insist on taking stinging nettle, at least opt for supplements that try to combine the advantages of several T boosters. The herb’s capacity to keep the hormone available should prove useful.

All in all, regardless of how supplement manufacturers market stinging nettle, testosterone boosting isn’t among its strong suits. While beneficial in a number of ways, it’s simply outclassed by other herbs in that aspect.


Alex Eriksson is the founder of Anabolic Health, a men’s health blog dedicated to providing honest and research-backed advice for optimal male hormonal health. Anabolic Health aspires to become a trusted resource where men can come and learn how to fix their hormonal problems naturally, without pharmaceuticals.

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