Acacetin: The Most Powerful Natural Aromatase Inhibitor Ever?

Aromatase inhibitors like acacetin play a crucial role in improving testosterone levels in men.

Aromatase is the enzyme that converts androgens into estrogens. As you may already know, androgens are the male hormones while estrogens are female hormones.

When aromatase creates too much estrogen in the body, it can cause problems like low testosterone levels, estrogen dominance, and even the dreadful gynecomastia, meaning breast growth in males. In other words, it's a big deal.

That's why it’s so important to prevent excessive aromatization in your body at all costs. For this natter, one of the most powerful natural aromatase inhibitors out there is acacetin.

But what exactly is acacetin? Can you find it in foods? Are there any acacetin supplements worth trying?

Keep reading to find out why acacetin is such an effective natural aromatase inhibitors. Of course, we'll also tell you about its other benefits—as well as possible side effects.



What is Acacetin?

Acacetin is a phytochemical from the flavonoid group with a wide range of pharmacological effects. This compound is produced by many plant species such as the Turnera diffusa (damiana), a plant often used as an herbal aphrodisiac.

Although acacetin is used in several dietary supplements, it still remains largely unknown and underappreciated by the general public.


Acacetin as an Aromatase Inhibitor

A study on Turnera diffusa revealed two compounds that could significantly suppress aromatase. This study focused on natural compounds with aromatase inhibitory activity.

The discovered compounds were acacetin and pinocembrin, both quite powerful even at minimal doses. Of course, this is awesome because sticking to low doses is often the best way to prevent unwanted side effects—while reaping all the benefits for your health at the same time.

In general, natural and synthetic aromatase inhibitors are used to treat low testosterone levels, estrogen dominance, and gynecomastia. In postmenopausal women, these compounds are also used in the treatment and prevention of breast cancer.


Fireman extinguishes a fire

Other Inhibitory Effects

Ravaging enzymes are like a wildfire. If you don't put it out, it will cause massive damage to anything and everything it touches.

Aside from aromatase, acacetin also has strong inhibitory effects against the following enzymes:


Modern medical equipment at testing laboratory

Acacetin Benefits

Its enzyme-inhibiting properties make acacetin a promising flavonoid with plenty of health benefits. Here are just a few of them:


Acacetin Side Effects

Right now, evidence is limited. The safety profile of acacetin is far from well-researched. In other words, the scientific community will need more clinical trials (and probably some 5-10 years) to determine the side effects of acacetin accurately. However, a few possible risks of using acacetin may include:

  • Skin irritation
  • Eye irritation
  • Respiratory irritation

The abovementioned hazards are based on aggregated GHS information from 30 companies, a unified system that looks into and classifies potential dangers of chemicals products. Most likely, these effects would be seen only in case of direct contact (for example, eye irritation if some acacetin gets in your eye, lung irritation if you inhale it, etc.)


The Bottom Line

If you’re looking for a powerful natural aromatase inhibitor, acacetin is a great choice. This verict is based on reliable studies on natural compounds with aromatase-blocking properties.

Not only acacetin is a powerful aromatase inhibitor, but it also has strong inhibitory effects on various other enzymes. You've seen the list. The potential health benefits are huge.

Acacetin appears to have cardioprotective, neuroprotective, anti-inflammatory, antidiabetic, antibacterial, and even anti-cancer effects.

By using pregnenolone cream or pregnenolone supplements, the levels of the compound in the body increases, and this brings about various benefits such as fatigue relief, and delay of the aging process.

While more research is needed to determine the exact side effects of this flavonoid, acacetin is already a promising compound.

To summarize, if your goal is to fight off estrogen dominance and bring your testosterone levels back to normal—acacetin could be a powerful solution. Keep in mind, though, that it's always better to confirm you have this kind of hormonal imbalance to begin with. Otherwise, acacetin won't be effective for you.


author

Alex Eriksson is the founder of Anabolic Health, a men’s health blog dedicated to providing honest and research-backed advice for optimal male hormonal health. Anabolic Health aspires to become a trusted resource where men can come and learn how to fix their hormonal problems naturally, without pharmaceuticals.





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