8 Best Epicatechin Supplements 2018 – The Myostatin Inhibitors Guide

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By using pregnenolone cream or pregnenolone supplements, the levels of the compound in the body increases, and this brings about various benefits such as fatigue relief, and delay of the aging process.

​To gain more skeletal muscle mass and boost testosterone too, you want to try the best epicatechin supplement. Epicatechin is a natural compound found in different foods such as dark chocolate and are natural myostatin inhibitors.

Epicatechin has numerous benefits for the body, and it’s understandable that you’d want some of those, but you can’t just binge on chocolate everyday hoping that you’re getting enough of the compound. That’s why we did the leg work for you and reviewed some of the best supplements containing it.

Best Epicatechin Supplements Comparison Table






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Olympus Labs

  • Green Tea Extract (600mg Epicatechin)
  • Punica Granatum Extract (Pomegranate)
  • Gallate-Enhanced Oligomers
CocoaVia Unsweetened Dark Chocolate


  • Dark Chocolate Extract
Viva Labs - The BEST Tasting Certified Organic Cacao Powder

Viva Labs

  • Organic Cacao Powder
Myokem Magnitropin


  • Paederia foetida extract
  • Cistanche deserticola extract
  • Gentiana lutea extract
  • Epicatechin
  • Black pepper extract
T6 Testosterone Booster – EPICENTER

Team Six Supplements

  • Magnesium Bisglycinate
  • Zinc
  • Epicatechin
  • Ashwagandha Extract
  • Laxosterone
  • Eurycoma longifolia (Tongkat Ali)
EPICAT 200 max

Gun Show Supplements

  • Epicatechin
EP1C Unleashed by Olympus Labs

Olympus Labs

  • Epicatechin (from green tea extract)
Follidrone 2.0 by Black Lion Research

Black Lion Research

  • Epicatechin
  • Ecklonia Cava


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    The Link Between Chocolate and Epicatechin

    Epicatechin is naturally present in some foods. Chocolate or cacao is one of the most popular sources of this amazing compound.

    Chocolate, dark chocolate in particular, is rich in flavonoids. It is a great natural source of flavonoids, especially of the subtype flavonols.


    The term cocoa flavanol and cocoa flavonoids are usually used interchangeably with cocoa extract. It is a rich natural source of epicatechin. It is a richer source of this active compound than any other dietary source such as green tea.​

    What Can Epicatechin Do for You?

    Epicatechin has many uses in the body. Among them are:

    • ​Promotes more NO (nitric oxide) production in the body. NO improves blood flow by widening the blood vessels.
    • Cocoa extract has immense benefits in the body. It affects numerous organs and improves their functioning.
    • It improves cellular responses to certain signaling compounds for enhanced functioning.
    • It can enhance the body’s natural testosterone production.

    The Science of Epicatechin: Proven Uses

    Numerous studies have been made to determine and prove the benefits of epicatechin.

    Study #1: ​Muscle Growth, a Myostatin Inhibitor

    The effect on skeletal muscle growth is one of the main reasons for the massive interest for epicatechin in recent years. One study was able to determine that epicatechin from dark chocolates inhibits myostatin. Low levels of myostatin protein are desirable because it leads to increased ability to build skeletal muscle mass. This means building more lean muscle size without any nasty side effects.

    If you want to know how to lower myostatin blocker, just remember that there is an important compound in the muscle-building process called follistatin. It regulates myostatin-signaling pathways, leading to lower action of myostatin inhibition that results in more muscle fiber building.

    In short, if you want to grow muscles, you have to control myostatin and enhance follistatin.

    Study #2: ​Appetite Control

    Another study found that dark chocolate can decrease appetite. This effect is due to the actions of epicatechin and procyanidins.

    In this study, daily intake of beverages containing non-alkalized cocoa mixture reduced the intake of food. This study used pizza eating as evaluation parameter.

    If you want to have less appetite for fattening foods like pizza, drink non-alkalized cocoa.

    Study #3: Epicatechin and Testosterone Levels

    One study explored the effect of epicatechin on testosterone levels. In vitro and in vivo experiments were done on Leydig cells (cells responsible for producing testosterone).

    Results found that catechins were able to increase the amount of testosterone in the blood of the study subjects (in this case, mice). Low-dose catechins were also found to increase the levels of GnRH stimulated LH.

    In short, daily low doses of catechins (such as epicatechins) stimulate the pituitary gland to produce hormones LH and GnRH. These hormones are necessary signals that will push the Leydig cells to produce more testosterone.

    Study #4: ​Insulin

    Cocoa extracts that contain epicatechin can help in promoting better blood flow and in improving the cells sensitivity to insulin.

    When the body absorbs epicatechin or (-) epicatechin, the cells becomes more responsive to the presence of insulin. That means more glucose gets to enter the cells. More glucose inside the cells means more energy for various processes.

    That effect alone opens up a huge range of better functions in the body. For example, more glucose in the Leydig cells will give them more energy to produce more testosterone. In the muscles, more glucose means more energy that enhances performance and muscle building.

    Study #5: Epicatechin and Blood Flow​

    Epicatechin in dark cocoa also affects blood flow. It enhances the production of nitric oxide. This compound widens the blood vessels, allowing greater blood flow to the tissues.

    In the same sense, more blood flow to the tissues and cells mean more nutrients to power cellular function. In the Leydig cells, better nutrition means more testosterone can be produced.

    epicatechin supplement myostatin inhibitor blood flow

    In the muscle tissues, better blood flow means better blood pressure and more nutrients to the muscles which helps the ability to build more lean muscle and helps control high blood pressure. This can also result in better performance during training, with enhanced performance and faster recovery.

    epicatechin supplement myostatin inhibitor cacao powder

    A Quick Look at the Best ​on the Market

    ​Here are some of the best on the market right now.


    ​This is an excellent natural supplement in the form of a highly concentrated dark chocolate extract. It has the highest natural dosage of this compound that is safe and effective in promoting higher testosterone levels and more muscle building. It also tastes great mixed as a drink!

    Viva Labs Organic Cacao Powder

    Natural source of epicatechin in the form of high quality Crillo cacao beans, certified organic. This is a good cheaper choice if you want to reap the benefits of epicatechin without spending too much money.

    Myokem Magnitropin​

    ​This supplement targets myostatin and contains additional herbs to increase anabolic effects, especially well suited for bodybuilding. Also one of the best testosterone boosters on the market.

    Epicenter Testosterone Supplement Laxogenin

    ​This product contains 6 ingredients that were trademarked and specially blended to produce an effective testosterone-booster and muscle-building supplement.

    EPICAT Myostatin Inhibitor

    ​This pure epicatechin extract is at 90% concentration, derived from natural sources such as green tea catechin. This product is formulated for both men and women.

    EP1C Unleashed

    Gain more muscle without steroids or PCT using this EP1C supplement. It also improves fat metabolism in the body for real, lean gains.

    Follidrone 2.0

    ​This one targets follistatin levels in the body to reduce myostatin actions. In addition to epicatechin it also contains a seaweed extract from Ecklonia cava. This one comes highly recommended as an potent muscle builder.

    The Best Epicatechin Supplement Reviews



    EP1LOGUE from Olympus Labs is the absolute leader among epicatechin supplements for one simple reason: it's packed with almost 600 mg of the stuff. This number outperforms all other products in the niche by a long shot.

    Additionally, EP1LOGUE is one of the few available Urolithin B-focused supplements. This flavonoid is synthesized in the human guts after consumption of foods rich in ellagitannins (like pomegranate, Punica Granatum) and is a powerful anabolic that ​stimulates muscle growth while simultaneously preventing muscle breakdown. 


    Last but not least, EP1LOGUE features a proprietary vasodilating and nitric oxide-boosting formulation of gallate-enhanced oligomers derived from grape seeds and marketed as 10x more powerful than the classic citrulline. This means better blood flow to the muscles - and thus enhanced delivery of epicatechin and urolithin B.

    Things We Liked

    • Synergistic and powerful components 
    • Enhanced bioavailability of epicatechin
    • Urolithin B to enhance anabolic results

    Things We Didn't Like

    • May cause a mildly upset stomach in sensitive customers

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    30% OFF your entire order at Olympus Labs!

    Supplementing with this product will provide 375 mg of cocoa flavonols. That also gives about 80 mg of epicatechin - one of the highest concentrations among natural supplements.

    In the body, the epicatechin affects NO production. More NO promotes more blood to the tissues. In the muscles, more blood flow means more nutrients for the cells to use in order to grow and multiply. You get to grow more muscles naturally by giving more nutrients to the muscles. Nothing artificial is fed to the cells since its an natural cacao extract, making it safer and more effective for muscle growth rate than synthetic myostatin inhibitors.

    CocoaVia Unsweetened Dark Chocolate

    Studies done on Cocoavia® showed that it improves cardiometabolic functioning. This effect is mainly from the enhancement on the production of NO in the body. It also helps improve body composition by improving fat metabolism.

    Things We Liked

    • Great flavor
    • Consumer Labs certified safe from cadmium contamination
    • Better blood flow

    Things We Didn't Like

    • Strong bitter taste for some, add sweetener if you need
    • May not dissolve well in cold water
    Viva Labs - The BEST Tasting Certified Organic Cacao Powder

    The cacao source of this product (Crillo cacao beans) is cultivated in the fertile, organic soils of the mountains in Peru. The plants grew in the most ideal, unspoiled environment, yielding top quality cacao powder.

    This product contains non-alkalized cacao powder. The powder is pure ground cacao nibs, which means that it has the highest concentration of antioxidants among cacao powders. Each serving contains:

    • 4 grams of fiber
    • 92 milligrams of magnesium

    Things We Liked

    • Bold cacao flavor
    • Gluten-free
    • QAI certified organic
    • Natural source of magnesium

    Things We Didn't Like

    • Does not dissolve well in cold water
    • Caffeine content may interfere with sleep in sensitive individuals

    Magnitropin boosts testosterone in the body. Testosterone affects skeletal muscle cell and stimulates more muscle size, which means it’s worth taking a look at if your goal is to build lean muscle and muscle strength.

    Magnitropins reduce myostatin levels, giving more opportunity for the muscle building process to happen. This also improves muscle growth, performance and recovery from resistance training.

    Myokem Magnitropin

    It boosts testosterone, thanks to the addition of a rare herbal extract. The herb is called Paederia foetida. The concentration is at a 20: ratio for optimum results.

    Things We Liked

    • Potent herbal ratio for testosterone boost and muscle gain
    • Results in better muscle performance and recovery
    • Increases hunger for faster weight gain (muscle)

    Things We Didn't Like

    • May cause intestinal problems for sensitive users
    T6 Testosterone Booster – EPICENTER

    If your goal is to gain more muscle naturally, this one works well. Epicenter’s testosterone supplement supports testosterone production. Its most notable testosterone-supporting ingredient is patent KSM-66 extract of Ashwagandha (Withania somnifera). This extract has been tested in numerous studies to be an effective natural testosterone booster, stress reducer, and muscle and strength gainer.

    Epicenter is also abundant in epicatechin (150 mg) that supports the muscle building process in the body. It also comes with trademarked ingredients- Laxogenin (30 mg), Longjack (Tongkat Ali, 100 mg), and the KSM-66 Ashwagandha (300 mg)- for ultimate muscle gains. Overall a very well balanced product that covers all the bases!

    Things We Liked

    • Promotes muscle building without water-retention
    • Comes in vegan capsules
    • No PCT needed

    Things We Didn't Like

    • A bit expensive than most other similar products

    EPICAT contains epicatechin derived from natural sources. Each capsule delivers 200 mg of 90% epicatechin extract.

    The main action of this supplement is controlling myostatin. It promotes dry gains i.e. building up without retaining water. It also increases muscle tone, strength, pumps and endurance. Combine with a good protein powder to fuel those gains.

    EPICAT 200 max

    Things We Liked

    • Can be used by both men and women looking to build muscles
    • Price worth the many benefits
    • Consistent results

    Things We Didn't Like

    • May cause some discomforts such as headaches in sensitive individuals
    • May cause rash in sensitive individuals
    EP1C Unleashed by Olympus Labs

    EP1C Unleashed contains high quality epicatechin, backed by lab analysis from a 3rd party tester.

    This product increases vascularity and fat oxidation which contributes to enhanced muscle strength and endurance.

    Things We Liked

    • No PCT required
    • Improves workout performance

    Things We Didn't Like

    • Results seen after a few weeks of continued use and training
    • More expensive reformulated product

    This product is manufactured by Black Lion Research which is know for creating unique and well formulated products.

    Follidrone contains Ecklonia Cava (EC) which is a form of seaweed (we discussed some other potential benefits from seaweeds in a previous article). This ingredient helps in increasing the levels of follistatin and keeping myostatin levels low. This will create the ideal condition for your body to build muscles naturally. It also contains a potent dose of Epicatechin for maximum benefits.

    Follidrone 2.0 by Black Lion Research

    Things We Liked

    • Great pre-workout pill
    • Improves stamina during workouts
    • Safe and effective, no side effects for most users

    Things We Didn't Like

    • Still need to be taken on non-workout days for continued effects

    What to Look for Concerning Epicatechin​

    Amazing results from numerous research studies created a huge interest in epicatechin. It can indeed promote greater muscle gains, better blood flow and higher testosterone levels.

    With the increased interest comes a surge of epicatechin containing supplements. A lot of these give larger-than-life promises and claims. Some are effective to some extent while some are just plain bust.

    epicatechin supplement myostatin inhibitor epicatechin structure

    Spending money on supplements that don't work will not only cost you money, it may also cost you your health. Some low-quality products may contain dangerous extracts or ingredients that will cause allergic reactions and other untoward side effects. Be very careful and read labels well.

    When you choose your supplement, you must consider these factors:

    • Quality of Epicatechin Source
      Not all epicatechin are highly effective. It still depends on the quality of the source of this amazing compound. Choose natural sources such as green tea and flavanol-rich cocoa. These sources must also be grown, harvested and prepared in safe, non-toxic conditions to avoid any untoward reactions. We like the idea of getting your epicatechin from a natural cacao extract which also contains other beneficial compounds.

    • Amount of Epicatechin
      Now, please take care when checking the dosages. The dosage must be within scientifically proven amounts to be effective. We aim for at least 100mg per serving. But less mg in natural form is also ok since natural product are often more potent because of the co-nutrients.

    • Added Ingredients
      Some supplements come with added herbal extracts such as Ashwagandha. This can be a benefit depending on your goals.

    Epicatechin is a naturally occurring compound and has a positive impact on the body. You can get epicatechin naturally from foods such as dark cocoa or from more concentrated supplements. When it comes to cacao, you have to choose those using cacao nibs or an extract for highest potency. Expect better results if you choose any of the products we have reviewed in this article.

    epilogue epicatechin


    We have 2 recommendations for various circumstances.

    EP1LOGUE is our favorite for those who wish to gain weight or build muscle using epicatechin, because of it's very high potency (600mg per serving) along with other beneficial ingredients for this purpose.

    Use our coupon code "ALEXE30" for 30% OFF your order of EP1LOGUE at Olympus Labs!

    Our favorite epicatechin supplement for overall health and longevity is CocoaVia®. It has the highest amount of cocoa derived natural epicatechin compared to other supplements and also contains many more beneficial compounds from cocoa such as cocoa flavanols and theobromine.

    CocoaVia Unsweetened Dark Chocolate

    CocoaVia® uses the patented Cocoapro® process that preserves majority of the phytonutrients in cocoa beans. A lot of research and studies were made on this product. The results proved that CocoaVia® promotes many health benefits such as improved cardiometabolic function.

    CocoaVia® is recommended for long-term use. It will help in strengthening the tissues and improving overall health.

    If looking for a budget-friendly choice, choose the regular cacao powder product. However, you would have to use A LOT more than the recommended serving in order to achieve the same level of benefits as CocoaVia®. This would also count towards a much higher calorie intake since regular cacao powder is higher in calories. 

    Product image credits: Amazon.com

    Alex Eriksson (Research Analysis)

    Alex Eriksson is the founder of Anabolic Health, a men’s health blog dedicated to providing honest and research-backed advice for optimal male hormonal health. Anabolic Health aspires to become a trusted resource where men can come and learn how to fix their hormonal problems naturally, without pharmaceuticals.